Modern Methods of Stereotactic Radiosurgery and Radiotherapy for the Treatment of Cushing Disease

Cushing's disease is caused by a pituitary tumor causing increased production of adrenocorticotropic hormone, which leads to chronic hypersecretion of cortisol through adrenal cortices. Endoscopic trans-sphenoidal adenomectomy is the first choice of treatment with greatest efficiency for the treatment of the disease. However, in the absence of remission or recurrence of hypercortisolism after neurosurgical resection (adenomectomy), as well as in cases when surgical intervention cannot be carried due to medical contraindications to surgical intervention, radiation treatment is used as an alternative or adjoining therapy. In this literature review the efficiency of different radiation techniques (the conventional and the modern techniques), as well as possible complications of modern methods of radiosurgery and radiotherapy have been looked for. © 2020 Wolters Kluwer Medknow Publications. All rights reserved.

Authors
Abdali A. 1, 2 , Abdali A. 1, 2 , Astaf`eva L. 1, 2 , Astaf`eva L. 1, 2 , Trunin Y. 1, 2 , Trunin Y. 1, 2 , Kalinin P. 1, 2 , Kalinin P. 1, 2 , Golanov A. 1, 2 , Golanov A. 1, 2 , Abdali B. 1, 2 , Abdali B. 1, 2 , Chmutin G. 1, 2 , Chmutin G. 1, 2 , Shkarubo A. 1, 2 , Shkarubo A. 1, 2 , Chaurasia B. 1, 2 , Chaurasia B. 1, 2
Journal
Neurology India
Publisher
Wolters Kluwer Medknow Publications
Number of issue
7
Language
English
Pages
S129-S133
Status
Published
Link
External link
DOI
10.4103/0028-3886.287663
Volume
68
Year
2020
Organizations
  • 1 N.N. Burdenko National Medical Research Center of Neurosurgery, Peoples' Friendship University of Russia, Moscow, Russian Federation
  • 2 Department of Neurological Diseases and Neurosurgery, Peoples' Friendship University of Russia, Moscow, Russian Federation
Keywords
Conventional-RT; Cushing disease; cyber-knife; fractionated stereotactic radiosurgery; gamma-knife; proton-therapy. stereotactic radiosurgery; radiotherapy
Date of creation
02.11.2020
Date of change
02.11.2020
Short link
https://repository.rudn.ru/en/records/article/record/64762/
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