Developing Techniques of Acoustic Microscopy for Monitoring Processes of Osteogenesis in Regenerative Medicine

Abstract: High-resolution ultrasonic imaging techniques are necessary for the non-invasive diagnostics of artificial cell-matrix systems. The results from experimental studies show these techniques are sensitive to variations in the elastic properties of biopolymer samples and can be used effectively to detect micro and macro voids and monitor processes of biodegradation in tissue-engineered constructs (TECs). © 2020, Allerton Press, Inc.

Authors
Petronyuk Y.S.1, 2 , Khramtsova E.A.1 , Levin V.M.1 , Bonartsev A.P. 3, 4 , Voinova V.I.3 , Bonartseva G.A. 4 , Muraev A.A. 5 , Asfarov T.F. 5 , Guseynov N.A. 5
Journal
Bulletin of the Russian Academy of Sciences: Physics
Number of issue
6
Language
English
Pages
653-656
Status
Published
Link
External link
DOI
10.3103/S1062873820060179
Volume
84
Year
2020
Organizations
  • 1 Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, 119334, Russian Federation
  • 2 Scientific and Technological Center of Unique Instrumentation, Russian Academy of Sciences, Moscow, 117342, Russian Federation
  • 3 Department of Biology, Moscow State University, Moscow, 119234, Russian Federation
  • 4 Bach Institute of Biochemistry, Fundamental Bases of Biotechnology Federal Research Center, Russian Academy of Sciences, Moscow, 119071, Russian Federation
  • 5 Institute of Medicine, People’s Friendship University of Russia, Moscow, 117198, Russian Federation
Keywords
Artificial life; Biodegradation; Biopolymers; Regenerative Medicine; Ultrasonic imaging; Acoustic microscopy; Artificial cell; Elastic properties; High resolution; Micro and macro; Monitoring process; Non-invasive diagnostics; Tissue engineered constructs; Diagnosis
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