Abiotic stress such as drought is a key environmental factor that affect morphology, phenology and plant biochemistry thereby significantly decreases productivity. In this regard, the present study was conducted evaluate the influence of various agrochemicals on the productivity of tomato cultivars in drip irrigation system under dry climatic conditions. The field experiment was conducted during 2018-19 at Caspian Agricultural Federal Scientific Center, Russian Academy of Sciences, Astrakhan region, Russia. The findings revealed that various agrochemicals had different effects on the productivity of all the tomato hybrids. The tomato hybrids ‘Cobra 26 F1’ and ‘Heinz 3402 F1’ produced significantly higher yields of 130.4 and 126.5 t/ha, respectively with Aminovite compared to other agrochemical treatments. The tomato hybrid ‘Sister F1’ produced significantly higher yield (106.45 t/ha) with agro-chemical SpeedFol Amino Calmag SL compared to other treatments of Agricola (103.30 t/ha), Aminofol NPK (98.90 t/ha), Aminovite (93.65 t/ha) and control (90.70 t/ha). The tomato variety ‘Rio Grande’ did not respond to agrochemicals and yields were significantly reduced from 66.30 t/ha under control to 56.65, 55.50, 41.25 and 35.20 t/ha with the application of SpeedFol Amino Calmag SL, Agricola, Amonovite and Aminofol NPK, respectively. Hence, nutrient program has a significant role in determining the tomato productivity. © 2020, Gaurav Society of Agricultural Research Information Centre. All rights reserved.