Nematic liquid crystal planar and smoothly-irregular waveguide structures were studied experimentally and by the computer modeling. Two types of optical smoothly-irregular waveguide structures promising for application in telecommunications and control systems are studied by numerical simulation: liquid crystal waveguides and thin film solid generalized waveguide Luneburg lens. Study of the behavior of these waveguide structures where liquid crystal layer can be used to control the properties of the entire device, of course, promising, especially since such devices are also able to perform various sensory functions when changing some external parameters, accompanied by a change in a number of their properties. It can be of interest to researchers not only in the field of the integrated optics but also in some others areas: nano-photonics, optofluidics, telecommunications, and control systems. The dependences of the attenuation coefficient (optical losses) of waveguide modes and the effective sizes (correlation radii) of quasi-stationary irregularities of the liquid-crystal layers on the linear laser radiation polarization and on the presence of pulse-periodic electric field were experimentally observed. An estimate was made of the correlation radii of liquid-crystal waveguide quasi-stationary irregularities. The obtained results are undoubtedly important for further research of waveguide liquid crystal layers, both from the theoretical point of view, and practical – in the organization and carrying out new experimental researches, for example, when developing promising integrated-optical LC sensors. © 2019, Institution of Russian Academy of Sciences. All rights reserved.