Purpose. To determine the orthodontic treatment relevance on the base of meta-analysis of the prevalence of dentoalveolar anomalies, and to compare the accuracy of 2D and 3D cephalometry to detect them. Materials and methods. Comprehensive literature search on the prevalence of dentoalveolar anomalies and comparison of 2D - and 3D-cephalometry results was carried out using two databases. After the selection of the selected criteria, 46 articles on prevalence and 20 articles containing studies on the comparison of teleroentgenogram and CBCT were taken for the analysis. The prevalence was estimated in two groups: analysis of the situation in different regions of the Russian Federation (RF) and prevalence in the world. Results. The analysis of statistical data showed a high prevalence of dentoalveolar anomalies, the highest figures were recorded in Colombia (88%) and Nigeria (88.2%), the lowest figure was recorded in Iran (29%). Among the RF subjects the highest value was found in Tyumen (89%), the lowest - in the Republic of North Ossetia-Alania (42.25%). The analysis of comparison of accuracy of teleroentgenogram and CBCT showed discrepancy in results of the carried-out works at different authors. Conclusion. Need for orthodontic treatment is quite high due to the high prevalence of dentoalveolar anomalies among the population. The advantages and disadvantages of 2D and 3D cephalometry are analyzed. For the final result in comparison to the accuracy requires further clinical and morphological studies.. © 2019 Russian Electronic Journal of Radiology. All rights reserved.