Optimization of the qualitative composition of liposomal drugs based on natural organomineral formations

Liposomal structures were developed on the basis of oil and water extracts of natural organomineral formations. These structures are natural compositions. The content of the main components in the preparations varies within the range of 20-25% of the lipophilic phase, 64-74% of the hydrophilic phase, 5-10% of the auxiliary component and the stabilizer on the phospholipid base is 1%. Phospholipids of natural origin were used as surface-active substances. The influence of hydrophilic and lipophilic auxiliary components on the content of neutral lipids in the surface lipid layer of the skin was studied. The developed preparations can be used as carriers of both hydrophilic and lipophilic active substances in pharmaceutical compositions, cosmetic and veterinary products on a natural basis. © 2017 Author(s).

Authors
Chzhu O.P. 1 , Shubenkova E.G.2
Conference proceedings
AIP Conference Proceedings
Language
English
Status
Published
DOI
10.1063/1.4998826
Number
020006
Volume
1876
Year
2017
Organizations
  • 1 Sochi Affiliated Branch RUDN University, 32, Kuibysheva St., Sochi, 354348, Russian Federation
  • 2 Omsk State Technical University, 11, Mira Pr., Omsk, 644050, Russian Federation
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/5384/
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Russian Journal of Organic Chemistry. Vol. 53. 2017.