The quality of life of 149 students of the Tver Medical College (118 girls and 31 young men) has been subjectively assessed using the Russian-language version of the 36- Item Short Form Health Survey (SF-36). The study has revealed the highest mean scores for physical functioning (91.29 ± 1.73 for the young men and 86.23 ± 1.70 for the girls) and the lowest mean scores for vitality (64.84 ± 3.85 and 56.20 ± 1.88 for the young men and the girls respectively). Compared to the girls, the young men's quality of life was statistically significantly higher according to the following scales: Vitality (p = 0.015), Role-Emotional (p = 0.005) and Mental Health (p = 0.007). The analysis of the correlations between the scales has shown that social functioning in the girls was statistically significantly dependent on all the physical and mental health components of the quality of life.