Proceedings - 29th European Conference on Modelling and Simulation, ECMS 2015.
European Council for Modelling and Simulation.
2015.
P. 675-681
Domino reaction of N-(cyanomethyl)-1,3-azolium quaternary salts with o-hydroxybenzaldehydes: Scope and limitations
A route towards chromenes, annulated with an imidazo[5,1-c][1,4]thiazine core through a base-promoted domino reaction of thiazolium quaternary salts, has been developed. The synthesised compounds show high cytotoxic activity against human tumour cell lines. This journal is © The Royal Society of Chemistry 2015.
Authors
Voskressensky L.G.
1
,
Festa A.A.
1
,
Storozhenko O.A.
1
,
Le T.A.
2
,
Nguyen V.T.3
,
Varlamov A.V.
1
Journal
Number of issue
16
Language
English
Pages
12442-12445
Status
Published
Link
Volume
5
Year
2015
Organizations
- 1 Organic Chemistry Department, Peoples' Friendship University of Russia, Miklukho-Maklaya st., 6., Moscow, 117198, Russian Federation
- 2 Department of Chemistry, Vietnam National University, 144 Xuan Thuy, Cau Giay, Hanoi, Viet Nam
- 3 Institute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam
Keywords
Cell culture; Cytotoxicity; Salts; Chromenes; Cytotoxic activities; Domino reactions; Hydroxybenzaldehydes; Quaternary salts; Synthesised; Tumour cells; Reaction kinetics
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