Global Journal of Pure and Applied Mathematics.
Research India Publications.
Vol. 12.
2016.
P. 2829-2838
Synthesis of quinolines via acid-catalyzed cyclodehydration of 2-(Tosylamino)chalcones
(Image presented) The acid-catalyzed cyclodehydration of (E)-3-[(2-tosylamino)phenyl]-1-(het)aiylprop-2-en-1-ones to 2-substituted quinolones was investigated. The reaction proceeds via the key step of (E,Z)-isomerization with subsequent intramolecular cyclization affording the target compounds in high yields. © 2016 Springer Science+Business Media New York.
Authors
Makarov A.S.1
,
Sorotskaja L.N.2
,
Uchuskin M.G.
1,
3
,
Trushkov I.V.
3,
4
Publisher
Латвийский институт органического синтеза Латвийской академии наук / Springer New York Consultants Bureau
Number of issue
12
Language
English
Pages
1087-1091
Status
Published
Link
Volume
52
Year
2016
Organizations
- 1 Perm State University, 15 Bukireva St., Perm, 614990, Russian Federation
- 2 Kuban State Technological University, 2 Moskovskaya St., Krasnodar, 350072, Russian Federation
- 3 Peoples’ Friendship University of Russia, 6 Miklukho-Maklaya St., Moscow, 117198, Russian Federation
- 4 Dmitry Rogachev Federal Research Center of Pediatric Hematology, Oncology and Immunology, 1 Samory Mashela St., Moscow, 117997, Russian Federation
Keywords
(E,Z)-isomerization; 2-(het)arylquinolines; Aldol condensation; Cyclodehydration; Friedlaender synthesis; Intramolecular cyclization
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Other records
RSC Advances.
Vol. 6.
2016.
P. 93881-93886