Reaction of enamino pyrrolidide and piperidide of 2,2-dimethyl-1,2,3,4-tetrahydrobenz[f]isoquinoline series with ninhydrin

Interaction of (4Z)-2,2-dimethyl-4-(2-oxo-2-pyrrolidin-1-ylethylidene)-1,2,3,4-tetrahydrobenz[f]isoquinoline with ninhydrin leads to annulation of an indeno[1,2-b]pyrrole ring. An analogous product is formed by replacing of the pyrrolidine ring with the piperidine ring. Further heating of the obtained glycol in the presence of AcOH leads to rearrangement with the formation of benz[f]isochromeno-[4',3':4,5]pyrrolo[2,1-a]isoquinoline hexacyclic system. © 2016, Springer New York LLC. All rights reserved.

Authors
Mikhailovskii A.G.1 , Korchagin D.V. 2 , Yusov A.S.1 , Gashkova O.V.1
Publisher
Латвийский институт органического синтеза Латвийской академии наук / Springer New York Consultants Bureau
Number of issue
10
Language
English
Pages
852-854
Status
Published
Volume
52
Year
2016
Organizations
  • 1 Perm State Pharmaceutical Academy, 2 Polevaya St., Perm, 614990, Russian Federation
  • 2 Peoples’ Friendship University of Russia, 6 Miklukho-Maklaya St., Moscow, 142432, Russian Federation
Keywords
(4Z)-2,2-dimethyl-4-(2-oxo-2-pyrrolidin-1-ylethylidene)-1,2,3,4-tetrahydrobenz[f]isoquinoline; Benz[f]isochromeno[4',3':4,5]pyrrolo[2,1-a]isoquinolin-9-one; Indeno[1,2-b]pyrrole
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/4200/
Share

Other records