Synthesis of 3,4-dihydroisoquinolines using nitroalkanes in polyphosphoric acid

A new method for the synthesis of 6,7-dimethoxy-3,4-dihydroisoquinoline based on the reaction of 2-(3,4-dimethoxyphenyl)ethan-1-amine (homoveratrylamine) with aliphatic nitro compounds in polyphosphoric acid (PPA) was developed. © 2019, Springer Science+Business Media, Inc.

Authors
Aksenov N.A. 1 , Malyuga V.V.1 , Abakarov G.M.2 , Aksenov D.A. 1 , Voskressensky L.G. 3 , Aksenov A.V. 1
Number of issue
5
Language
English
Pages
1047-1051
Status
Published
Volume
68
Year
2019
Organizations
  • 1 North Caucasus Federal University, 1A ul. Pushkina, Stavropol, 355009, Russian Federation
  • 2 Dagestan State Technical University, 70 ul. Imama Shamilya, Makhachkala, 367010, Russian Federation
  • 3 Peoples’ Friendship University of Russia, 6 ul. Miklukho-Maklaya, Moscow, 117198, Russian Federation
Keywords
6,7-dimethoxy-3,4-dihydroisoquinoline; alkaloids; nitro compounds; phenylethylamines; polyphosphoric acid
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