The article considers topical for the conditions and problems of the functioning of a knowledge-intensive enterprise, the development of its forms and methods of organization of production, taking into account the life cycle of the product and the enterprise. The purpose of the work: to develop a model for selecting and developing forms and methods for organizing knowledge-intensive production, taking into account the features and conditions of functioning of a modern science-intensive enterprise. The author's model of choosing the type, methods and forms of organization of high technology production by the criterion of resource optimization taking into account the enterprise's potential is pro science-intensive enterprise, life cycle theory, theory of fuzzy sets.