Material-associated bone resorption

A number of similar macrophage responses to the implantation of various osteoplastic materials into bone defects in humans and laboratory animals have been demonstrated in the present article based on the retrospective analysis of the archival histological material (2008–2016). The presence of osteoplastic materials in a bone regenerate has led to the emergence of giant cells of foreign bodies and osteoclastogenic cells both on the surface of the material and neoformed bone with its subsequent resorption. It was suggested to name this phenomenon “material-associated bone resorption”. © 2019, Privolzhsky Research Medical University. All rights reserved.

Authors
Bonartsev A.P.1, 2 , Muraev A.A. 3 , Deyev R.V.4 , Volkov A.V. 5, 6
Journal
Sovremennye Tehnologii v Medicine
Publisher
Nizhny Novgorod State Medical Academy
Number of issue
4
Language
English
Pages
26-33
Status
Published
Link
External link
DOI
10.17691/stm2018.10.4.03
Volume
10
Year
2018
Organizations
  • 1 Department of Bioengineering, Lomonosov Moscow State University, 1/12 Leninskie Gory, Moscow, 119991, Russian Federation
  • 2 Laboratory of Microorganism Nitrogen Fixation, Bach Institute of Biochemistry of the Russian Academy of Sciences, Federal Research Center, “Fundamentals of Biotechnology” of the Russian Academy of Sciences, 33/2 Leninskiy Prospect, Moscow, 119071, Russian Federation
  • 3 Department of Maxillofacial Surgery and Surgical Dentistry, Peoples’ Friendship University of Russia, 6 Miklukho-Maklaya St, Moscow, 117198, Russian Federation
  • 4 Department of Histology, Pathologic Anatomy, and Medical Genetics, I.P. Pavlov Ryazan State Medical University, 9 Vysokovoltnaya St, Ryazan, 390026, Russian Federation
  • 5 Department of Pathologic Anatomy, Peoples’ Friendship University of Russia, 6 Miklukho-Maklaya St, Moscow, 117198, Russian Federation
  • 6 Laboratory for Studies of the Connective Tissue, N.N. Priorov National Medical Research Center of Traumatology and Orthopaedics, Healthcare Ministry of Russia, 10 Priorov St, Moscow, 127299, Russian Federation
Keywords
Bone resorption; Bone tissue; Giant cells of foreign bodies; Osteoclasts; Osteoplastic materials; Regenerative medicine; Tissue engineering
Date of creation
04.02.2019
Date of change
04.02.2019
Short link
https://repository.rudn.ru/en/records/article/record/36580/
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