Psychodermatology: a molecular link between psoriasis and anxiety disorder

This article describes premises for the development of psychodermatology. An analysis of research literature and data is presented based on the example of psoriasis and anxiety disorder. Protein molecules with altered concentrations in patients with psoriasis and anxiety disorder compared to controls are identified (chemokine [C-C motif] ligand 2, corticotropin-release hormone, growth hormone 1, leptin, and tumor necrosis factor with increased concentration and brain-derived neurotrophic factor with decreased concentration). All molecules are secretory peptides. In the future, the information obtained may make it possible to pursue an in-depth study of the molecular mechanisms underlying psychodermatology.

Authors
Klimov E. 1, 2, 3 , Tretiakov A.1 , Rudko O. 1 , Soboleva A. 4 , Danilin I. 5 , Korsunskaya I. 4 , Sobolev V. 2, 4, 6
Publisher
NLM (Medline)
Number of issue
4
Language
English
Pages
179-183
Status
Published
Volume
27
Year
2018
Organizations
  • 1 Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian Federation
  • 2 University Diagnostic Laboratory, Moscow, Russian Federation
  • 3 Center for Experimental Embryology and Reproductive Biotechnologies, Moscow, Russian Federation
  • 4 Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, Moscow, Russian Federation
  • 5 Peoples ' Friendship University of Russia, Moscow, Russian Federation
  • 6 I. I. Mechnikov Research Institute for Vaccines and Sera RAMS, Moscow, Russian Federation
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