Expression of genes for thioredoxin 1 and thioredoxin 2 in multidrug resistance ovarian carcinoma cells SKVLB

The expression of genes for thioredoxin isoforms Trx1 and Trx2 was studied in sensitive SKOV-3 and resistant SKVLB human ovarian carcinoma cells. The development of doxorubicin resistance was accompanied by a significant increase in the expression of TRX1 gene and less pronounced increase in TRX2 gene expression. © Springer Science+Business Media, Inc. 2007.

Authors
Kalinina E.V. 2, 3 , Chernov N.N. 3 , Saprin A.N.1 , Kotova Ya.N.1 , Gavrilova Yu.A.1 , Chermnykh N.S.1 , Shcherbak N.P.1
Journal
Bulletin of Experimental Biology and Medicine
Publisher
New York Consultants BureauSpringer / Автономная некоммерческая организация Издательство Российской академии медицинских наук
Number of issue
3
Language
English
Pages
301-303
Status
Published
Link
External link
DOI
10.1007/s10517-007-0316-3
Volume
144
Year
2007
Organizations
  • 1 Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Russian Federation
  • 2 Institute of Cytochemistry and Molecular Pharmacology, Moscow, Russian Federation
  • 3 Peoples’ Friendship University of Russia
Keywords
Doxorubicin; Drug resistance; Thioredoxin
Date of creation
19.10.2018
Date of change
25.04.2023
Short link
https://repository.rudn.ru/en/records/article/record/3211/
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