Quantitative determination of metabolites in human urine by 1 H NMR spectroscopy

Conditions for registration of urinary 1H NMR spectra have been optimized in order to achieve maximal accuracy of quantitative analysis. Urinary samples from patients with acute pancreatitis have been investigated and spectral data of identified urinary metabolites and results of their quantitative determination are given. Employment of 1H NMR spectra is perspective for the development of new laboratory diagnostic methods. © MAIK Nauka 2008.

Authors
Kolokolova T.N.1 , Sergeev N.M.1 , Korol'kov A.Yu. 2
Journal
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry
Number of issue
4
Language
English
Pages
418-425
Status
Published
Link
External link
DOI
10.1134/S1990750808040136
Volume
2
Year
2008
Organizations
  • 1 Lomonosov Moscow State University, School of Chemistry, Leninskie Gory 1, Moscow 119992, Russian Federation
  • 2 Russian University of People's Friendship, School of Medicine, Moscow, Russian Federation
Keywords
1H NMR spectroscopy; Acute pancreatitis; Metabolites; Urine
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