Wound healing potential of chitosan and N-sulfosuccinoyl chitosan derivatives

Comparative study of chitosan wound healing properties and its synthesized derivatives in MC-100 gel was carried out using the model of experimental full thickness skin wounds. It was determined that N-sulfosuccinoyl chitosan derivatives added into the gel in a concentration of 0. 05% possess the higher wound healing activity in comparison with other chitosan derivatives and decrease the half-healing period of wounds 2-3 times in comparison with the control. © 2010 Pleiades Publishing, Ltd.

Authors
Alekseeva T.P.1 , Rakhmetova A.A. 2 , Bogoslovskaya O.A.1 , Olkhovskaya I.P.1 , Levov A.N. , Il'ina A.V.3 , Varlamov V.P.3 , Baitukalov T.A.4 , Glushchenko N.N.1
Journal
Biology Bulletin
Number of issue
4
Language
English
Pages
339-345
Status
Published
Link
External link
DOI
10.1134/S1062359010040023
Volume
37
Year
2010
Organizations
  • 1 Institute of Energy Problems of Chemical Physics, Russian Academy of Science, Leninskii pr. 38/2, Moscow 119334, Russian Federation
  • 2 Peoples' Friendship University of Russia, Miklukho-Maklaya 6, Moscow 117198, Russian Federation
  • 3 Center Bioinzeneria, Russian Academy of Science, pr. 60 let Oktyabrya 7/1, Moscow 117312, Russian Federation
  • 4 Familiprix Lasalle, rue Airlie, Lasalle, Montreal-Ouest 9316, Canada
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