Russian Journal of Genetics.
Vol. 48.
2012.
P. 63-69
Reaction of 3, 3-dimethyl-and 3-spirocyclohexyl-tetrahydroisoquinolines with alkynes
It has been found that 2, 3, 3-trimethyl-1-phenyl- and 1, 2-dimethyl-3-spirocyclohexyltetrahydro-isoquinolines react with activated alkynes in methanol with cleavage of the tetrahydropyridine ring to give methoxybenzyl- and methoxyethylbenzenes, and in boiling acetonitrile form N-butenoyl derivatives from N-methylspirocylohexyltetrahydroisoquinoline by its reaction with acetylacetylene. © 2012 Springer Science+Business Media, Inc.
Authors
Voskressensky L.G.
1
,
Bol'Shov A.V.
1
,
Borisova T.N.
1
,
Rozhkova Yu.S.2
,
Sorokina E.A.
1
,
Varlamov A.V.
1
Publisher
Латвийский институт органического синтеза Латвийской академии наук / Springer New York Consultants Bureau
Number of issue
3
Language
English
Pages
453-457
Status
Published
Link
Volume
48
Year
2012
Organizations
- 1 Peoples' Friendship University of Russia, 6 Miklukho-Maklaya St., Moscow 117198, Russian Federation
- 2 Institute of Technical Chemistry, Ural Branch of the Russian Academy of Sciences, 3 Acad. Korolev St., Perm 614013, Russian Federation
Keywords
Cleavage of the tetrahydropyridine ring; N-demethylation; Tandem transformations; Tetrahydroisoquinoline
Date of creation
19.10.2018
Date of change
19.10.2018
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Other records
Chemistry of Heterocyclic Compounds.
Латвийский институт органического синтеза Латвийской академии наук / Springer New York Consultants Bureau.
Vol. 48.
2012.
P. 514-524