Antiherpetic activity of L-Lysine-α-oxydase in different dosage forms

The antiviral effect of different medicinal forms on base of L-lysin-α-oxidase (LO) in treatment of experimental keratits and skin diseases induced by herpes simplex virus type 1 (HSV-1) at the rabbits was examined. Treatment with gel form of LO was more effective in comparison with water solution form of LO. This effect was tested by morphological, histological and immunoblotting methods in dynamics of viral disease.

Authors
Selytsheva A.A. 1 , Alexeev S.B. 1 , Smirnova I.P. 1 , Podboronov V.M. 1
Journal
Antibiotiki i Khimioterapiya
Number of issue
1
Language
Russian
Pages
9-12
Status
Published
Link
External link
Volume
48
Year
2003
Organizations
  • 1 N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Russian Academy of Medical Sciences, People's Friendship University of Russia, Moscow, Russian Federation
Keywords
Herpes simplex virus type 1 (HSV-1); Herpetic keratitics; L-lysin-a-oxidase; Skin herpetic diseases; Treatment of herpes virus infections
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/23/
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