Interaction between Endocrine and Exocrine Pancreas

The pancreas plays a key role in the endocrine system of animals, as well as in the digestion and absorption of nutrients. The exocrine and endocrine portions of the pancreas are structurally separated from each other, however, multiple studies suggest the anatomical and functional unity between them. While previously, the interactions of these two portions received less attention, nowadays the pancreas is considered as a single organ consisting of functionally interlinked components, which coordinates endocrine and exocrine responses. The review addresses the latest data indicating the functional relationship and reciprocal influence of the endocrine and exocrine pancreatic portions. In addition, we consider the impact of SARS-CoV-2 infection on pancreatic function.