Нутритивная поддержка детей с детским церебральным параличом:опыт применения отечественного энтерального питания

Nutritional support for children with cerebral palsy: experience in the use of oedematous enteral nutrition in children

Introduction. Increased protein and energy requirements, high levels of inflammatory response, osteopenia, and endogenous intoxication syndrome in patients with cerebral palsy determine the need to use therapeutic enteral mixtures with a metabolic focus (EMF) in their nutrition.Aim. Evaluate the clinical efficacy and tolerability of the use of domestic therapeutic nutrition (nutritive support (NS) – ESMN Detoxifying Protein Cocktail NUTRIO and Bone Tissue Cocktail (protein) in children with cerebral palsy.Materials and methods. A comparative prospective study was conducted at the State Healthcare Institution of the Tyumen Region, the Children’s and Rehabilitation Center Nadezhda. 39 children with cerebral palsy aged 3 to 18 years with a severity of motor impairment of GMFCS III-V were observed. All patients were divided into 4 groups depending on their age and nutritional support: 1stmain (n = 5) aged 3–8 years with NS; 1stcontrol (n = 5) without NS; 2ndmain (n = 21) aged 9–17 years with NS; 2ndcontrol (n = 8) without NS. The study period was 30 days. Before and After the study, the general condition of the children, nutritional status, anthropometry, densitometry, as well as blood parameters and markers of inflammation and intoxication were assessed. Results. Against the background of nutritional support, the following was observed: statistically significant increase in body weight, height, z-score of body weight, mainly due to skeletal muscle mass; an increase in the level of protein and albumin in the blood; a decrease in markers of intoxication and inflammation; an increase in bone mineral density. Conclusions. The Protein Detoxification Cocktail NUTRIO and Bone Tissue Cocktail (protein) in diet therapy for children with cerebral palsy is effective in correcting their nutritional status, preventing the development of osteopenia, reducing inflammation and intoxication and improving the quality of life. © Пилат ТЛ, Тропина ЕП, Змановская ВА, Живаева ОН, Аникина ВС, Кузнецова ЮГ, Ляпунова ТВ, Семин ДА, 2025 References