In an era of intensifying global food insecurity, agricultural supply systems confront unprecedented destabilization driven by interconnected geopolitical, climatic, and logistical risks. Against this critical backdrop, Sino- Russian agricultural cooperation crystallizes as a geostrategic imperative, capitalizing on complementary resource endowments—Russia’s vast arable expanses and China’s technological prowess—to fortify transnational food resilience architectures. This research critically investigates the evolution of intelligent supply chain within this bilateral agro-economic nexus through triangulated empirical case studies and system dynamics modeling. Rigorous analysis not only maps operational efficiencies across production, processing, and distribution nodes but also identifies key structural impediments, spanning infrastructural deficiencies, regulatory asymmetries, and technological adoption gaps. Building upon these diagnostics, we propose a suite of actionable optimization strategies: digital twin integration for real-time logistics coordination, blockchain-enabled traceability frameworks, and AI-driven risk mitigation protocols. The study’s contributions are twofold. First, it advances bilateral integration through evidence-based governance frameworks that harmonize policy alignment with targeted investment pathways. Second, it engineers implementable solutions—modular technology toolkits and adaptive financing mechanisms—that structurally reinforce food security infrastructures against systemic shocks. These insights catalyze transformative policy design while establishing scalable partnership models for cultivating sustainable agricultural ecosystems within increasingly volatile global markets. Ultimately, this work illuminates how strategic cross-border agroindustrial symbiosis can transcend traditional trade paradigms to underpin collective food sovereignty. © 2025 by the author(s). Published by Nan Yang Academy of Sciences Pte.