Results of International, Double-Blind, Randomized, Placebo-Controlled, Phase IIa Study of Interleukin-1 Blockade with RPH-104 (Goflikicept) in Patients with ST-Segment-Elevation Myocardial Infarction (STEMI)

Abbate A. , Van Tassell B. , Bogin V. , Markley R. , Pevzner D.V. , Cremer P.C. , Meray I. , Privalov D.V. , Taylor A. , Grishin S.A. , Egorova A.N. , Ponomar E.G. , Lavrovsky Y. , Samsonov M.Y. , Pisaryuk A. , Babaeva L. , Zyuryaev I. , Kalimulin D. , Lapin O. , Mekhriakov S. , Popov N. , Kalashnikov I. , Duhanina E. , Osmanova S. , Kornilov E. , Zubova E. , Safarian V. , Selezneva N. , Savelieva E. , Privalova O. , Shogenov Z. , Novosadov V. , Agirov M. , Nilk R. , Fedash A. , Yurkovskiy A. , Kotova A. , Staroverov I. , Mayorov V. , Lonchakova O. , Rozanov D. , Yakushin S. , Seleznev S. , Pravkina E. , Pereverzeva K. , Ivanova G. , Turlington J.S. , Thomas G. , Talasaz A.H. , Golino M. , Buono M.G.D. , Marawan A. , Damonte J.I.

Circulation

Lippincott Williams & Wilkins

7

English

580-582

Published

External link

10.1161/CIRCULATIONAHA.124.069396

150

2024

• ¹ Department of Medicine, University of Virginia, Charlottesville, United States
• ² Department of Internal Medicine, Virginia Commonwealth University, Richmond, United States
• ³ Cromos Pharma, LLC, Portland, OR, United States
• ⁴ Emergency Cardiology Department, National Medical Research Center for Cardiology, The Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation
• ⁵ Department of Cardiovascular Medicine Heart, Vascular and Thoracic Institute, Cleveland Clinic, OH, United States
• ⁶ Department of Internal Medicine, Peoples' Friendship University of Russia N.a. Patrice Lumumba, Moscow, Russian Federation
• ⁷ Cardiology and Intensive Therapy Department, City Clinical Hospital No. 51, Moscow Healthcare Department, Russian Federation
• ⁸ R-Pharm JSC, Medical Department, Moscow, Russian Federation
• ⁹ R-Pharm Overseas Inc, San Diego, CA, United States

cytokine; inflammation; myocardial infarction