International Journal of Environmental Research.
Springer Science and Business Media Deutschland GmbH.
Vol. 18.
2024.
Preparation of Tritium Labeled Dexamethasone Phosphate and Its Application to Assess the Affinity of Ligands for Glucocorticoid Receptors
Abstract: The possibility of introducing tritium into dexamethasone and dexamethasone phosphate using the thermal activation method was demonstrated. The affinity of ligands for glucocorticoid receptors has been successfully assessed using labeled compounds. © Pleiades Publishing, Ltd. 2024.
Authors
Badun G.A. ,
Zhidkova E.M. ,
Chernysheva M.G. ,
Enikeev A.D. ,
Yakubovskaya M.G. ,
Lesovaya E.A.
Journal
Number of issue
4
Language
English
Pages
514-521
Status
Published
Link
Volume
66
Year
2024
Organizations
- 1 Faculty of Chemistry, Moscow State University, Moscow, 119991, Russian Federation
- 2 Blokhin Russian Cancer Research Center, Ministry of Health of Russia, Kashirskoe shosse 24, Moscow, 115478, Russian Federation
- 3 Friendship University of Russia, ul. Miklukho-Maklaya 6, Moscow, 117198, Russian Federation
- 4 Pavlov Ryazan State Medical University, Ministry of Health of Russia, Vysokovol’tnaya ul. 9, Ryazan, 390026, Russian Federation
Keywords
glucocorticoid; glucocorticoid receptor; radioligand binding assay; selective glucocorticoid receptor agonists; tritium
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Proceedings of the Steklov Institute of Mathematics.
Vol. 325.
2024.
P. S168-S178