Postoperative Chemotherapy After Surgical Resection of Metachronous Metastases of Colorectal Cancer: A Systematic Review

Currently, 6 months of perioperative or adjuvant chemotherapy (ACT) is a standard treatment option after radical surgical removal of metachronous metastases in patients with metastatic colorectal cancer (CRC). Data show that ACT improves relapse-free survival in such patients, although no difference in overall survival rate was observed. We perform a systematic review to evaluate the efficacy of adjuvant chemotherapy after radical resection of metachronous metastases in CRC. © 2023, World Journal of Oncology. All rights reserved.

Authors
Evdokimova S. , Kornietskaya A. , Bolotina L. , Sidorov D. , Kaprin A.
Journal
World Journal of Oncology
Publisher
Elmer Press
Number of issue
1
Language
English
Pages
26-31
Status
Published
Link
External link
DOI
10.14740/WJON1568
Volume
14
Year
2023
Organizations
  • 1 P. Hertsen Moscow Oncology Research Institute, Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, Moscow, 125284, Russian Federation
  • 2 Department of Chemotherapy, P. Hertsen Moscow Oncology Research Institute, Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, Moscow, Russian Federation
  • 3 Abdominal Oncology, City Clinical Oncological Hospital, No. 1, Moscow, 105005, Russian Federation
  • 4 Urology Department, Peoples’ Friendship University of Russia, Moscow, 117198, Russian Federation
Keywords
Adjuvant chemotherapy; Colorectal cancer; Liver metastases; Metachronous metastases; Radical resection
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