Nephrotoxicity of combination drug therapy in metastatic renal cancer; [Нефротоксичность комбинированной лекарственной терапии метастатического рака почки]

The review covers reduced kidney function in the context of renal cell carcinoma. According to international studies, some patients already have chronic kidney disease at time of disease onset. Surgical treatment leads to a decrease in the total number of functioning nephrons. Drug therapy causes several adverse events including nephrotoxicity. The review discusses the problem of using combination regimens in patients with solitary kidney. © 2023 ABC-press Publishing House. All rights reserved.

Authors
Titov K.S. , Shutov E.V. , Alimov A.A. , Lebedev S.S. , Kirichek A.A. , Zapirov G.M.
Journal
Onkourologiya
Publisher
ABC-press Publishing House
Number of issue
3
Language
Russian
Pages
153-162
Status
Published
Link
External link
DOI
10.17650/1726-9776-2023-19-3-153-162
Volume
19
Year
2023
Organizations
  • 1 S.P. Botkin City Clinical Hospital, Moscow Healthcare Department, 5 2nd Botkinskiy Proezd, Moscow, 125284, Russian Federation
  • 2 Peoples’ Friendship University of Russia Named After Patrice Lumumba, 6 Miklukho‑Maklaya St., Moscow, 117198, Russian Federation
  • 3 Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia, Build. 1, 2/1 Barrikadnaya St., Moscow, 125993, Russian Federation
Keywords
acute kidney injury; chronic kidney disease; immunotherapy; renal cell carcinoma; targeted therapy
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