Practical guidelines on drug treatment of primary operable breast cancer

Breast cancer (BC) treatment implies an integrated approach that involves inclusion of surgical techniques, radiation therapy, chemotherapy, endocrine therapy, targeted therapy, and in some cases immunotherapy in the treatment plan, while selection of treatment tactics depends on the tumor biological subtype, neoplastic process extension, and somatic status of the patient. The paper provides analysis of Russian clinical guidelines and advanced treatment regimens for primary operable BC that are based on the principle of case-by-case selection in each clinical situation considering the disease stage, tumor molecular subtype and the goals set by an expert specialist. © 2023, LLC MMA MediaMedika. All rights reserved.