Molecular structure and ultrasound-assisted synthesis of the diazacrown derivative containing 2,3,4,6-tetraaryl-γ piperidone

A 14-membered azacrown ether, namely, 23,25-diphenyl-7-tosyl-4,10-dioxa-7-aza-2(2,6)-piperidina-1(2,1),3(1,2)-dinaphthalenacyclodecaphan-24-one, was successfully synthesized in a short period of time and with a reasonable yield using ultrasonic vibration. The obtained compound containing a polyether chain, an N-tosyl group and a piperidone ring seems promising biologically active substance and ligand for chelating with metal ions. © 2023

Authors
Dao N.T. , Do T.T. , Pham T.T.T. , Tran V.T.T. , Khrustalev V.N. , Le A.T.
Publisher
Royal Society of Chemistry
Number of issue
5
Language
English
Pages
711-713
Status
Published
Volume
33
Year
2023
Organizations
  • 1 Faculty of Chemistry, VNU University of Science, Vietnam National University, Thanh Xuan, Hanoi, 100000, Viet Nam
  • 2 Faculty of Pharmacy, Thai Nguyen University of Medicine and Pharmacy, Thai Nguyen, 250000, Viet Nam
  • 3 Peoples Friendship University of Russia (RUDN University), Moscow, 117198, Russian Federation
  • 4 N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, 119991, Russian Federation
  • 5 Faculty of Agricultural Technology, VNU University of Engineering and Technology, Cau Giay, Hanoi, 100000, Viet Nam
Keywords
azacrownophane; N-tosyl; piperidone; polyether chain; ultrasonic vibration; X-ray
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