Objective: To clarify the frequency and pattern of intrauterine pathology in a non-selective cohort of patients participating in assisted reproductive technologies (ART) programs. Materials and methods: The frequency of intrauterine pathology was explored in 973 patients aged 23 to 44 years who had participated in ART programs. The diagnosis was finally verified with office or routine hysteroscopy and histomorphological examination. The incidence of endometrial hyperplastic processes (EHPs) in assessing its relationship to the use of previous treatment with ART was determined separately in groups of patients younger and older than 35 years. Results: Intrauterine pathology was found in 38% of all the patients involved in ART programs. In patients with initially suspected uterine factor infertility, its frequency increased up to 68%. The pattern of verified intrauterine pathology predominated with EHPs, accounting for 44%. Conclusion: In the non-selective population of patients participating in ART programs, the women with intrauterine pathology showed a preponderance of EHPs in its pattern, which manifested themselves as glandular hyperplasia and endometrial polyps. © A group of authors, 2022.