Features of clinical and histological diagnosis of recurrent melanocytic nevus

Despite the prevalence of melanocytic skin nevi (MSN) in the population, the management of patients especially with multiple melanocytic nevi remains ambiguous. According to some studies, after removal, the frequency of recurrence of MSN ranges from 11.7% to 20% after shave biopsy and destructive physical methods, respectively. Recurrent melanocytic skin nevus is a histological mimic of skin melanoma and requires careful diagnosis. The article presents a clinical case of recurrent melanocytic nevus that was first diagnosed with an optical device Handyscope (FotoFinder; Germany) and Handyscope3 app based on artificial intelligence (AI) and then confirmed by subsequent histological examination. Since it is impossible to predict which MSN will relapse and considering that the recurrence of melanocytic nevi does not always correlate with amount of lesion excision and a surgeon’s experience, it is necessary to develop clear criteria on the feasibility and removal method of melanocytic nevi, including the use of AI. All removals of melanocytic nevi should be carried out only with histological examination with further mandatory long-term follow-up. © 2022, MDV Group. All rights reserved.

Authors
Gaydina T.A. , Patsap O.I. , Dvornikov A.S.
Publisher
Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт морфологии человека"
Number of issue
4
Language
Russian
Pages
48-52
Status
Published
Volume
11
Year
2022
Organizations
  • 1 Pirogov Russian Scientific Research Medical University, Moscow, Russian Federation
  • 2 Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency, Moscow, Russian Federation
  • 3 Scientific and Educational Resource Center “Innovative Technologies of Immunophenotyping, Digital Spatial Profiling and Ultrastructural Analysis”, RUDN University, Moscow, Russian Federation
Keywords
melanocytic skin nevus; melanoma of the skin; recurrent melanocytic skin nevus
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