Pharmacology of a new medicinal form, phenasal granules

Experiments on mice and rats were made to study a new medicinal form, phenasal granules given per os and to compare it with ground tablets and powder of phenasal as regards the intestinal content, absorption capacity, anthelminthic activity and toxicity. The intestinal content and absorption capacity of phenasal were medicinal form-dependent. The highest anthelminthic activity was exhibited by phenasal granules. Acute toxicity of powder, ground tablets and granules of phenasal administered to mice and rats per os remained the same.