Экспериментальные исследования биологического дренажа на основе костного коллагена "ксенопласт", насыщенного сульфатиро ванными гликозаминогликанами и l-аргинином

Experimental research of biological drainage "Xenoplast" based on osteal collagen, saturated with sulfated glycosaminoglycans and L-arginine 1%

Current item presents the results of morphological investigation of «Xenoplast» - a biological drainage based on osteal collagen, saturated with sulfated glycosaininoglycans and L-arginine 1%. In experimental glaucoma surgery the drainage was implanted between superficial and deep scleral flaps in filtering zone of rabbit eyes (8 animals, 16 eyes). Control animals underwent implantation of clear demineralized osteal collagen into operation zone. The follow-up period was 3 months after operation. The obtained data showed; 1) the equal high biocompatibility and resistance against biodestruction in experimental and control groups in long follow-up terms; 2) osteal collagen-based material «Xenoplast», saturated with sulfated glycosaminoglycans and L-arginine 1% (experiment) improves trophies and mechanical properties of sctera in implantation area due to formation of neogenic vessels and integration with neighbouring sclera.