ГЕНОТИПИРОВАНИЕ ПО ГЕНАМ GPI//а И ПРОТРОМБИНА ПАЦИЕНТОВ С ДИСЛИПИДЕМИЯМИ, СТРАДАЮЩИХ ГИПЕРТОНИЧЕСКОЙ БОЛЕЗНЬЮ И ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА

ALLELIC DISTRIBUTION OF GPI//A GENE AMONG DISLIPIDAEMIA PATIENTS WITH ARTERIAL HYPERTENSION AND CORONARY HEART DISEASE

As well known presence of defective integrin receptors is the reason of serious diseases such as coronary atherosclerosis and coronary heart disease. The distribution of gene region coding type I// β-subunit of GPI//a glycoprotein end gene region coding protrombin among dislipidaemia patients genomes was described in current paper. The correlation between presences of defective PLA2 alleles, defective G20210A alleles and higher probabilities of coronary heart disease and arterial hypertension for such patients was demonstrated here. As was shown dislipidaemia patients with defective PLA2 alleles can be characterized with higher risk of complication of coronary heart disease and arterial hypertension and require additional medical treatments.