Metastasis-directed therapy in testicular cancer

Purpose of review This review highlights the importance of addressing testicular cancer metastasizing beyond the retroperitoneum, focusing on multidisciplinary approaches and advances in treatment. Recent findings Recent literature emphasizes on the evolving landscape of metastasis-directed therapy, including surgical interventions, chemotherapy regimens, and radiation therapy. The effectiveness of these treatments varies depending on the site of metastasis, with various approaches improving survival rates and quality of life for patients. We divide our review in an organ-specific manner and focus on chemotherapeutic, surgical, and radiation therapy approaches pertaining to each site of metastasis. Summary Our review suggests the pressing need for continued research to refine and personalize treatment strategies. These efforts are important for enhancing clinical practice, ultimately leading to better outcomes for patients with metastatic testicular cancer.

Authors
Pandit Kshitij 1 , Yuen Kit 1 , Puri Dhruv 1 , Yodkhunnatham Nuphat 1 , Millard Frederick2 , Bagrodia Aditya 1
Publisher
Lippincott Williams & Wilkins
Language
English
Status
Published
Year
2024
Organizations
  • 1 Department of Urology
  • 2 Department of Medicine, UC San Diego School of Medicine, La Jolla, California, USA
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