Minimizing population health loss due to scarcity in OR capacity: validation of quality of life input

Abstract Objectives A previously developed decision model to prioritize surgical procedures in times of scarce surgical capacity used quality of life (QoL) primarily derived from experts in one center. These estimates are key input of the model, and might be more context-dependent than the other input parameters (age, survival). The aim of this study was to validate our model by replicating these QoL estimates. Methods The original study estimated QoL of patients in need of commonly performed procedures in live expert-panel meetings. This study replicated this procedure using a web-based Delphi approach in a different hospital. The new QoL scores were compared with the original scores using mixed effects linear regression. The ranking of surgical procedures based on combined QoL values from the validation and original study was compared to the ranking based solely on the original QoL values. Results The overall mean difference in QoL estimates between the validation study and the original study was − 0.11 (95% CI:  -0.12 - -0.10). The model output (DALY/month delay) based on QoL data from both studies was similar to the model output based on the original data only: The Spearman’s correlation coefficient between the ranking of all procedures before and after including the new QoL estimates was 0.988. Discussion Even though the new QoL estimates were systematically lower than the values from the original study, the ranking for urgency based on health loss per unit of time delay of procedures was consistent. This underscores the robustness and generalizability of the decision model for prioritization of surgical procedures.

Authors
Gravesteijn B.Y. 1, 2 , Van Hof K.S.1 , Krijkamp Eline3 , Asselman Franck4 , Leemans C.R.5 , Van Alphen A.M.1 , Van der Horst Henriëtte6 , Widdershoven Guy7 , Baatenburg de Jong Leonie8 , Lingsma Hester1 , Busschbach Jan1 , Baatenburg de Jong Rob1
Publisher
BioMed Central
Number of issue
1
Language
English
Pages
31
Status
Published
Volume
23
Year
2023
Organizations
  • 1 Erasmus University Medical Center
  • 2 Department of Obstetrics & Gynaecology
  • 3 Erasmus University Medical Center, currently employed by the Erasmus School of Health Policy and Management, Erasmus University
  • 4 Amsterdam University Medical Centers
  • 5 Amsterdam University Medical Centres, Cancer Center Amsterdam, Vrije Universiteit
  • 6 Amsterdam University Medical Centers Vrije Universiteit
  • 7 Amsterdam University Medical Centres, Vrije Universiteit
  • 8 University of Amsterdam
Keywords
validation; Value based health care; prioritization; surgery; Decision modeling; quality of life; Theory of Medicine/Bioethics; Statistical theory and methods; Statistics for Life Sciences; medicine; health sciences
Date of creation
01.07.2024
Date of change
01.07.2024
Short link
https://repository.rudn.ru/en/records/article/record/109046/
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