Mechanisms of extraribosomal protein biosynthesis in eukaryotes

The appearance of newly synthesized proteins in the total protein fraction of a cell-free protein-synthesizing system not containing ribosomes and mRNA and enriched with polyenzyme complexes of aminoacyl-tRNA synthetases and corresponding proteins is proved experimentally. For modeling of extraribosomal protein biosynthesis we proposed a molecularr polyenzyme mechanism of protein biosynthesis on a protein matrix.

Authors
Mal'tsev A.V. 1, 2, 3 , Firsova A.A. 1, 2, 3 , Il'ina E.V. 1, 2, 3 , Korneev V.N. 1, 2, 3
Journal
Бюллетень экспериментальной биологии и медицины\r\nКлеточные технологии в биологии и медицине (Bulletin of Experimental Biology and Medicine)
Publisher
New York Consultants BureauSpringer / Автономная некоммерческая организация Издательство Российской академии медицинских наук
Issue number
4
Language
English
Pages
347-353
State
Published
Link
External link
DOI
10.1023/A:1016237719170
Volume
133
Year
2002
Organizations
  • 1 Institute of Physical and Chemical Medicine, Russian Ministry of Health, Russian Federation
  • 2 Russian University of People's Friendship, Moscow, Russian Federation
  • 3 Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Russian Federation
Keywords
Aminoacyl-tRNA synthetase; Biosynthesis; Eukaryotes; Peptides; Protein
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