Analysis of the State of Coronary Arteries in Patients With Acute Coronary Syndrome in Dependence on the Integrin beta-3 Gene Polymorphism

Aim of this study was to analyze the state of coronary arteries in patients with acute coronary syndrome according to polymorphism of integrin beta-3 (ITGB3) gene. All patients were divided into 2 groups: carries and non-carries of PLA2 allele. Carriers of PLA2 allele compared with noncarriers had lesser grades of coronary artery stenoses but greater number of involved arteries. Carriers had more repetitive acute coronary events.