Multisystem inflammatory syndrome in children associated with new coronavirus infection (Covid-19): Clinical and morphological comparisons

Multisystem Inflammatory Syndrome in Children (MIS-C) associated with new coronavirus infection (COVID-19), with signs of Kawasaki disease (KD) and toxic shock syndrome, well-defined diagnostic criteria, is the most severe manifestation of COVID-19 in pediatric patients. MIS-C is analogous to the cytokine storm in children with COVID-19. The article presents a clinical observation of a child with MIS-C with a lethal outcome. Clinical and anamnestic data, the results of laboratory and instrumental research allowed to diagnose MIS-C in a 2-year-old girl with full KD form. Autopsy results, detailed microscopic examination, which revealed systemic vasculitis of small and medium-sized vessels, inflammatory infiltrates in different organs, are presented, clinical and morphological comparisons are made. © 2020, Pediatria Ltd.. All rights reserved.

Авторы
Ovsyannikov D.Yu. 1, 2 , Novikova Y.Yu.1, 2 , Abramov D.S.3 , Angel A.E.2 , Glazyrina A.A. 1, 2 , Kantemirova M.G. 1, 2 , Kislyakov A.N.2 , Kryshova E.S.2 , Kurbanova S.Kh. 2 , Petryaykina E.E. 1, 2, 4 , Rtishchev A.Yu. 1, 2, 4 , Tigai Z.G. 1 , Kharkin A.V.2 , Shalatonin M.P. 2
Номер выпуска
6
Язык
Русский
Страницы
119-126
Статус
Опубликовано
Том
99
Год
2020
Организации
  • 1 Рeoples’ Friendship University of Russia, Moscow, Russian Federation
  • 2 Morozov Children’s City Clinical Hospital, Moscow, Russian Federation
  • 3 National Scientific-Practical Center of Pediatric Hematology, Oncology and Immunology n.a. D. Rogachev, Moscow, Russian Federation
  • 4 Pirogov Russian National Research Medical University, Moscow, Russian Federation
Ключевые слова
Clinical observation; COVID-19; Kawasaki disease; Pathological anatomy; Pediatric multisystem inflammatory syndrome
Дата создания
20.04.2021
Дата изменения
20.04.2021
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/72577/