Introduction: Population morbidity and coverage with follow-up and preventive medical examinations are the criteria for assessing preventive measures. Objective: To analyze the dynamics of morbidity and the coverage with preventive medical examinations and health screening of the population of the Udmurt Republic in 2002–2022. Material and methods: Over the period 2002–2022 we studied incidence and prevalence rates in the adult population (per 1,000 population) and the coverage with follow-up (per 1,000 patients) and preventive medical examinations (%) using such research methods as literature review, statistical, time series, mathematical, and comparative analysis. Results: Both the incidence and prevalence rose in the Udmurt Republic with the growth rates of 12.6 % and 22.3 %, respectively. The negative growth of incidence was established in the town of Glazov (–4 %) and the Alnashsky (–10.96 %), Vavozhsky (–23.1 %), Votkinsky (–24.6 %), Kiyasovsky (–35.4 %), and Mozhginsky (–9 %) districts; that of prevalence – in Glazov (–0.15 %) and the Vavozhsky (–27.9 %), Votkinsky (–3.2 %), and Uvinsky (–18.3 %) districts. The coverage with preventive examinations in the region did not change significantly (from 84.1 % to 84.5 %) while that with followup examinations grew by 140.55 %. In Glazov and the Alnashsky, Vavozhsky, Votkinsky and Kiyasovsky districts with decreasing incidence rates, the coverage with reventive medical examinations dropped on average to 68.64 % (from 87.82 % in the year 2002) whereas the coverage with follow-up examinations increased by 133.1 %. The decrease in incidence in the Mozhginsky district from 643.5 to 585.6 per 1,000 population was observed against the background of an increase in the coverage of the population with preventive examinations from 91.1 % to 94.7 % and follow-up examinations by 147.5 %. Conclusions: In 2002–2022, both incidence and prevalence rates and the coverage of population with follow-up examinations increased in the Udmurt Republic. The coverage with preventive medical examinations did not change significantly. Incidence rates decreased in the town of Glazov and the Alnashsky, Vavozhsky, Votkinsky, Kiyasovsky, and Mozhginsky districts, which allows us to predict an improvement in epidemic processes in other administrative territories. © 2024 Federal Center for Hygiene and Epidemiology. All rights reserved.