Anaplastic thyroid cancer: a case series study; [Анапластический рак щитовидной железы: анализ серии случаев]

We conducted a retrospective analysis of the treatment of anaplastic thyroid cancer (ATC) in 24 patients between May 2014 and July 2021. The study included 24 patients aged 22 to 81 years, 15 (62.5 %) female and 9 (37.5 %) male. Among them, 14 (58.3 %) underwent surgical treatment. In the postoperative period, 8 (33.3 %) patients received a course of radioiodine therapy with a total dose (TD) of 3-4 GBq. Seven (29.2 %) patients underwent external beam radiation therapy (EBRT), while in 2 (8.3 %) cases, chemotherapy (CT) with carboplatin was administered concomitantly with EBRT. Four (16.7%) patients were treated with lenvatinib. Nine (37.5 %) patients did not receive treatment due to various reasons. In untreated patients, overall survival (OS) was 5.8 ± 0.5 months. For patients who received treatment, OS was 9.6 ± 1.0 months. p < 0.00095. © 2023 Izdatel'stvo Meditsina. All rights reserved.