Various approaches to DNA sonification are given: based on the mathematical analysis of DNA parameters and the effect of ultrasound DNA cleavage in solution. Parametric manifestations of DNA with the presence of a fractal structure are also given. The effect of fractality and the sonification of genetic information is discussed. The prospects of the bionic approach for man-machine-environment systems and interfaces of the future are discussed. The main message is bionic ergonomics, the principle of nature-like technologies. An example of the principle of simplifying the perception of complex genetic information in interfaces is given in the algorithms for visualization and sonification of nucleotide sequences. The study was conducted at the intersection of biomechanics, bionics and bioinformatics.