MICRORNAS AS BIOMARKERS OF CARDIOVASCULAR DISEASES

The fact that microRNAs play an important role in the development and pathogenesis of cardiovascular disease is beyond doubt. This article provides a brief overview of recent data that relate to microRNA expression in various cardiovascular diseases. Detecting significant changes in the level of expression of these molecules in various diseases means that microRNAs can be considered to be potential biomarkers of human pathologies including heart failure. Studying the relationship between the mechanisms of cardiovascular disease and the level of expression of a variety of microRNAs, as well as establishing their exact relationships with the genes is an urgent problem and requires further research.

Authors
Romakina V.V.1 , Zhirov I.V.1, 2 , Nasonova S.N.1 , Zaseeva A.V.1 , Kochetov A.G. 1, 3 , Liang O.V. 3 , Tereshchenko S.N. 1, 2
Journal
Publisher
KlinMed Consulting
Number of issue
1
Language
Russian
Pages
66-71
Status
Published
Volume
58
Year
2018
Organizations
  • 1 Natl Med Res Ctr Cardiol, Inst Cardiol, Moscow, Russia
  • 2 Russian Med Acad Postgrad Educ, Med Acad Continuing Educ, Moscow, Russia
  • 3 Peoples Friendship Univ Russia, RUDN Univ, Moscow, Russia
Keywords
chronic heart failure; microRNA; microRNA expression; diagnostics; biomarker
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