Immunorehabilitology: Sources, Present and Perspectives. From Immunotherapy to Personalized Targeted Immunorehabilitation

Development and introduction of modern clinical diagnostic tests (that allow to evaluate the functional system of immune homeostasis) into medical practice, a huge body of evidence on the leading role of the immune system in pathogenesis most acute and chronic diseases and even identification of specific nosological forms of immune-mediated diseases forced the scientists to search and develop new tools and techniques that have therapeutic effects on the impaired immune homeostasis and restore it to the normal state. The introduction of a novel concept -immunorehabilitation -was an impetus for the accumulation of new knowledge and a catalyst for research in clinical immunology. The first papers on this topic were published over 30 years ago [ 6, 8-11, 15, 17]. It was Revaz Sepiashvili who breathed life into the concept of immunorehabilitation. He was lucky to be at its origin. He became not only the founder of the brand new scientific field -immunorehabilitation, but also the founder of a new medical science -immunorehablitology. In this paper, the author returns to the roots and recalls the way that medical science has gone before coming to understand immunorehablitology and tells readers about current successes and its development prospects.