Widespread of scleroma. A rare clinical case

Scleroma is a chronic infectious disease characterized by developing inflammation nye granulomas, mainly of the upper respiratory tract, with subsequent scarring. The reasons for the development of scleroma remain unclear, but it is generally accepted that the gram-negative coccal bacterium Klebsiella rhinoscleromatis (pas-Volkovich’s loch - Frisch) is the causative agent of this disease. Endemic in the spread of scleroma is considered There are tropical and temperate zones such as Africa, Asia, Eastern Europe, South America and Central America. Features of development scleroma in the present case and the complexity of the diagnosis caused by atypical, the rapid development of the disease, the greater prevalence of the process (including the orbit), with the transition to the soft tissues of the cheek bone and upper jaw, which is not typical for scleroma. The process was primarily localized in the left maxillary sinus and mimicked sinusitis. The presence of radicular cysts and darkening of the left maxillary sinus on radiographs, taking into account the clinical picture of the disease, were interpreted incorrectly, which led to the establishment of an incorrect diagnosis and subsequent surgical interventions. More targeted and consistent examination of histo-the logical material obtained after three surgical interventions made it possible to identify the characteristic signs scleroma, establish the correct diagnosis and prescribe effective treatment. In our case, we applied Ciprofloxacin course for 3 months at a maximum daily dose of 2000 mg in combination with probiotics. During treatment, it was noted a significant improvement in the patient’s well-being, facial pains became less intense, a decrease in the volume of ma tissues of the left cheek and improved nasal breathing. © 2021, Media Sphera Publishing Group. All rights reserved.

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  • 1 Peoples’ Friendship University of Russian, Moscow, Russian Federation
  • 2 International Medical Center, «ON-Clinics», Moscow, Russian Federation
  • 3 Federal State Budget Scientific Institution, «Research Institute of Human Morphology», Moscow, Russian Federation
Atypicalpitic course; Scleroma; Treatment with ciprofloxacin with a positive effect
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