Evaluation of Hypothermic and Analgesic Effects of Local Anesthetics Based on Non-Contact Thermography and Registration of Evoked Responses

Literature provides information that local hypothermia has a nonspecific anti-inflammatory effect. Aim: to assess the intensity of the hypothermic effect of application drugs with local anesthetic properties and determine the tropism of local anesthetics to the tissues of the maxillofacial region. The study of temperature indicators from the oral mucosa was carried out using an infrared thermometer before, immediately, 1, 2 and 5 minutes after the application of a gel based on 10% lidocaine, 20% benzocaine and a gel based on a chelate complex organogermanium compounds with guanine. Skin temperature was determined using a thermal imager before and after injections of 4% articaine with an epinephrine 1:100000 and 1:200000. To evaluate the effectiveness of injectable forms of local anesthetics, a study of thermal evoked potentials was performed using a Contact heat evoked potential stimulator. A study of the cooling effect of application of anesthesia showed that immediately after application in all groups, aspecially in nonanesthetic gel chelate organogermanium complex immediately after application 32.92 °C, 1 minute - 32.84 °C, 3 minutes - 33.67 °C, 5 minutes - 34.69 °C. The use of an increased content of the vasoconstrictor at the periphery of the injection site results in depression of the microvasculature, as indicated by a decrease in the temperature background. According to CHEPS registration 4% articaine is somewhat more effective for anesthetizing teeth and bones, as it often causes deeper anesthesia and 3% mepivacaine without epinephrine is physiologically more suitable for working with soft tissues. In the presence of acute inflammatory diseases of the oral mucosa or chronic and / or recurrent processes, the drug of choice may be a chelate organogermanium gel. It is necessary to take into account not only its tropism to tissues, but also its hypothermic effect. © 2021, Journal of International Dental and Medical Research. All Rights Reserved.