Rational treatment of patients with functional dyspepsia [Рациональный подход к лечению пациентов с функциональной диспепсией]

Functional dyspepsia is one of the most common functional disorders of the gastrointestinal tract, which resulted from impaired motor skills, visceral hypersensitivity, increased mucosal permeability, disorders of the autonomic nervous system, etc. There is no specific therapy for this disease, which often leads to the irrational use of various groups of drugs. Drug therapy is recommended only during periods of symptoms. The main options of pharmacotherapy include the use of proton pump inhibitors, phytotherapeutic drugs, eradication therapy of Helicobacter pylori. Against the background of possible motor disorders, prokinetics are also one of the possible treatment options, but cisapride has long been withdrawn from sale due to cardiotoxicity, the use of domperidone and metoclopramide is limited due to side effects, especially with long-term therapy, so currently the only prokinetic that can be used in everyday clinical practice is itopride. In refractory cases, tricyclic antidepressants and psychotherapeutic approaches are another effective treatment option. © 2021. Journal of Plant Nutrition and Fertilizers. All rights reserved.

Authors
Kazakov A.S. 1 , Zyryanov S.K. 1 , Ushkalova E.A. 1 , Nasretdinova E.K.2
Number of issue
8
Language
Russian
Pages
982-985
Status
Published
Volume
93
Year
2021
Organizations
  • 1 People's Friendship University of Russia (RUDN University), Moscow, Russian Federation
  • 2 Children's Medical Center Office of the President of the Russian Federation, Moscow, Russian Federation
Keywords
Functional dyspepsia; Meta-analysis; Prokinetics; Rational pharmacotherapy
Date of creation
16.12.2021
Date of change
16.12.2021
Short link
https://repository.rudn.ru/en/records/article/record/76989/
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