Dietary therapeutic and preventive food products in complex therapy of gastroinal tract diseases associated with helicobacter pylori

Introduction. The paper presents modern literature and clinical research data on the efficacy and safety of dietary therapeutic and prophylactic foods in the complex therapy of diseases associated with Helicobacter pylori. Aim. To assess the efficacy and safety of the use of dietary therapeutic and prophylactic food products in the complex therapy of diseases of the gastrointestinal tract associated with Helicobacter pylori. Materials and methods. To evaluate the efficacy of dietary therapeutic and prophylactic food products such as Vegetable Puree Soup with Herbs and Oatmeal, Oatmeal Porridge with Herbs and Flax Seed, Protein-Sea Buckthorn Cocktail (LEOVIT Nutrio LLC), the main group of patients with gastrointestinal diseases (n = 41) was formed, which was further divided into four subgroups. Each of three subgroups received one specialty food product, and the fourth subgroup received all three products. Changes in complete blood count were evaluated using Sysmex XT-2000i analyzer, those in proteinograms – using SAS1, SAS2 protein fraction analyser and those in metabolic liver disorders, lipid profile and glucose level – using Konelab PRIME 30i (Thermo Fisher Scientific) analyzer. All parameters were studied three times: Before use, 14 and 60 days after use of the products. Results and discussion. After 14 days, complaints of lack of appetite decreased in the main group, discomfort in the epigastrium, feeling of heaviness and nausea decreased. After 60 days, 100% of patients reported no heartburn, belching, nausea, pain, rumbling in the abdomen, appetite and stool returned to normal. There was a marked significant (p <0.05) decrease in the level of alpha-1 globulin against the background of an increase in albumin, a decrease in the concentration of CRP and ESR, the levels of leukocytes and neutrophils in all subgroups of the main group after 60 days. Conclusions. The investigated products are safe, no adverse reactions were noted, including the phenomena of intolerance and allergies, and are recommended for use in diseases of the gastrointestinal tract associated with Helicobacter pylori. © 2021, Remedium Group Ltd. All rights reserved.

Authors
Pilat T.L.1 , Kuzmina L.P.1, 2 , Bezrukavnikova L.M.1 , Kolyaskina M.M. 1, 2 , Korosteleva M.M. 3, 4 , Ismatullaeva S.S. 3 , Khanferyan R.A. 3
Publisher
Remedium Group Ltd
Number of issue
15
Language
Russian
Pages
176-183
Status
Published
Volume
2021
Year
2021
Organizations
  • 1 Izmerov Research Institute of Occupational Health, 31, Budyonnyy Prospect, Moscow, 105275, Russian Federation
  • 2 Sechenov First Moscow State Medical University (Sechenov University), 8, Bldg. 2, Trubetskaya St, Moscow, 119991, Russian Federation
  • 3 Peoples’ Friendship University of Russia, 6, Miklukho-Maklai St, Moscow, 117198, Russian Federation
  • 4 Federal Research Center for Nutrition, Biotechnology and Food Safety, 2/14, Ustinsky Proezd, Moscow, 109240, Russian Federation
Keywords
Dietary therapeutic and prophylactic food; Gastrointestinal diseases; Helicobacter pylori; Inflammatory process; Pain syndrome
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