LYMPHOID ORGANS IN EXPERIMENTAL PROSTATE CARCINOGENESIS

Histological methods were used to study structural changes in the thymus and pelvic lymph nodes of SVA mice on day 18 after transplantation of ascitic Ehrlich tumor into the prostate gland. On day 18 of the experiment, a complete replacement of normal tissue with atypical cells, disorganization of the thymus structure - an increase in the volume of cortical matter, the number of epithelial reticular cells, a decrease in the number of immunoblasts in the cortical and cerebral matter was found. In the lymph nodes, on day 18, metastases were determined, follicular reaction was detected, increased transport function, against the background of an increase in the number of lymph vessels in the prostate.