The value of herbal medicine in the treatment of acute tonsillopharyngitis of non-streptococcal genesis

The purpose of the study. To establish the effectiveness of symptom reduction and preventive action of the herbal drug Tonsilgon N (HD) as monotherapy for exacerbations of chronic tonsillitis/pharyngitis in adult patients. Material and methods. The study included 60 adult male and female patients aged 18 to 60 years with an established diagnosis of acute tonsillopharyngitis. In total, each patient underwent 5 visits. Visit 1-enrollment in the study and beginning of HD mono-therapy, Visit 2-on Day 7, Visit 3-on Day 14 and completion of HD monotherapy, Visit 4-on Day 60 and Visit 5-on Day 180. The diagnosis of the disease and the examination of the patient was carried out on the basis of anamnesis, general clinical and ENT examination, palpation of regional lymph nodes. The severity of the clinical signs was evaluated on the basis of the symptom score. The general condition of the patient was also evaluated using a visual analogue scale (VAS) and the number of exacerba-tions of tonsillopharyngitis during the observation period. Results. The number of exacerbations of chronic tonsillitis and episodes of ATP for 6 months after the end of treatment decreased 4.8 times compared to the previous period. During the course of treatment (14 days), complaints of patients with ATP (general health and/or fatigue, pain when swallowing, headache, cough, burning sensation, a lump in the throat, hoarseness, pain and dry-ness in the throat, difficulty swallowing) had a pronounced tendency to regression. Improvement was also noted on examination and clinical evaluation. According to the results of the analysis of the evaluation of general condition according to the VAS (according to the standard technique in cm), there was a significant improvement both during the treatment period by 2.2 times, and during the observation period (180 days) from the period of Visit 2 to Visit 4 by 31.3 times. Conclusion. The use of HD as monotherapy for non-streptococcal ATP has shown its high efficiency. The possibility of using Ton-silgon N was shown as a prophylactic agent that reduces the number of exacerbations of inflammatory diseases in the pharynx during the period after the treatment course. © 2020, Media Sphera Publishing Group. All rights reserved.

Authors
Tarasova G.D. 1 , Mirzabekyan E.V.2 , Kirichenko I.M. 3
Number of issue
5
Language
Russian
Pages
65-70
Status
Published
Volume
85
Year
2020
Organizations
  • 1 National Medical Research Center of Otorhinolaryngology of the Federal Medical and Biological Agency, Moscow, Russian Federation
  • 2 Hospital of the Russian Academy of Sciences, Moscow, Russian Federation
  • 3 Peoples' Friendship University of Russia, Moscow, Russian Federation
Keywords
Acute tonsillopharyngitis; Prevention; Tonsilgon N
Date of creation
20.04.2021
Date of change
20.04.2021
Short link
https://repository.rudn.ru/en/records/article/record/72893/
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