Features of the course of bronchial asthma in children with a history of bronchopulmonary dysplasia [Особенности течения бронхиальной астмы у детей с бронхолегочной дисплазией в анамнезе]

Introduction. The development of bronchial asthma in children is often associated with previous bronchopulmonary dysplasia. Objective. To study the features of the clinical course of bronchial asthma in children with a history of bronchopulmonary dysplasia. Children characteristics and research methods. The test group consisted of 77 patients with a history of bronchial asthma and bronchopulmonary dysplasia. The control group included 81 patients with bronchial asthma without bronchopulmonary dysplasia. The patients were diagnosed in accordance with the Classification of clinical forms of bronchopulmonary diseases in children. The level of immunoglobulins was determined by enzyme immunoassay. Results. The patients with bronchial asthma and bronchopulmonary dysplasia demonstrated an earlier manifestation of bronchial asthma, a mild course and a rare need for inhaled bronchodilators, significant disproportions in changing the level and frequency of allergic inflammation markers - frequent eosinophilia with a lower increase in total IgE. The developed stage-by-stage program of examination and management of children with bronchial asthma and bronchopulmonary dysplasia will improve the diagnosis and treatment of patients with these diseases. Conclusion. The pediatricians shall take into account the identified clinical features of bronchial asthma in children with a history of bronchopulmonary dysplasia in their practice. © 2020 National Academy of Pediatric Science and Innovation. All rights reserved.

Authors
Ovsyannikov D.Yu. 1 , Agarkov N.M.2 , Modestov A.A. 3 , Chicherin L.P.4 , Kravchuk D.A. 1
Publisher
National Academy of Pediatric Science and Innovation
Number of issue
4
Language
Russian
Pages
101-107
Status
Published
Volume
65
Year
2020
Organizations
  • 1 Peoples Friendship University, Moscow, Russian Federation
  • 2 South-West State University, Kursk, Russian Federation
  • 3 National Medical Research Center for Children’s Health, Moscow, Russian Federation
  • 4 Semashko National Research Institute of Public Health, Moscow, Russian Federation
Keywords
Bronchial asthma; Bronchopulmonary dysplasia; Children; Clinical features
Date of creation
20.04.2021
Date of change
20.04.2021
Short link
https://repository.rudn.ru/en/records/article/record/72818/
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